Simona Distinto

Affiliations

Department of Life and Environmental Sciences University of Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.

Publications (21)

Targeting HIV-1 RNase H:

Viruses

Avec: Angela Corona , Ester Ballana , Simona Distinto , Dominga Rogolino , Claudia Del Vecchio , Mauro Carcelli , Roger Badia , Eva Riveira-Muñoz , Francesca Esposito , Cristina Parolin , José A Esté , Nicole Grandi , Enzo Tramontano

Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B.

ACS medicinal chemistry letters

Avec: Rita Meleddu , Antonella Fais , Benedetta Era , Sonia Floris , Simona Distinto , Antonio Lupia , Filippo Cottiglia , Alessia Onali , Erica Sanna , Daniela Secci , Giulia Atzeni , Laura Demuru , Pierluigi Caboni , Donatella Valenti , Elias Maccioni

2-(2-Methyl-2-nitrovinyl)furan but Not Furvina Interfere with

International journal of molecular sciences

Avec: Diana Oliveira , Anabela Borges , Reinaldo Molina Ruiz , Zenaida Rodríguez Negrín , Simona Distinto , Fernanda Borges , Manuel Simões

New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII.

ACS medicinal chemistry letters

Avec: Rita Meleddu , Simona Distinto , Filippo Cottiglia , Rossella Angius , Pierluigi Caboni , Andrea Angeli , Claudia Melis , Serenella Deplano , Stefano Alcaro , Francesco Ortuso , Claudiu T Supuran , Elias Maccioni

Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production.

Antiviral research

Avec: Angela Corona , Elisa Fanunza , Cristiano Salata , Melody Jane Morwitzer , Simona Distinto , Luca Zinzula , Cinzia Sanna , Aldo Frau , Gian Luca Daino , Marina Quartu , Orazio Taglialatela-Scafati , Daniela Rigano , StPatrick Reid , Alì Mirazimi , Enzo Tramontano

Coumarins from

Journal of enzyme inhibition and medicinal chemistry

Avec: Benedetta Fois , Simona Distinto , Rita Meleddu , Serenella Deplano , Elias Maccioni , Costantino Floris , Antonella Rosa , Mariella Nieddu , Pierluigi Caboni , Claudia Sissi , Andrea Angeli , Claudiu T Supuran , Filippo Cottiglia

Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids.

ACS medicinal chemistry letters

Avec: Rita Meleddu , Vilma Petrikaite , Simona Distinto , Antonella Arridu , Rossella Angius , Lorenzo Serusi , Laura Škarnulytė , Ugnė Endriulaitytė , Miglė Paškevičiu Tė , Filippo Cottiglia , Marco Gaspari , Domenico Taverna , Serenella Deplano , Benedetta Fois , Elias Maccioni

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors.

Journal of enzyme inhibition and medicinal chemistry

Avec: Serena Massari , Angela Corona , Simona Distinto , Jenny Desantis , Alessia Caredda , Stefano Sabatini , Giuseppe Manfroni , Tommaso Felicetti , Violetta Cecchetti , Christophe Pannecouque , Elias Maccioni , Enzo Tramontano , Oriana Tabarrini

Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from

Journal of enzyme inhibition and medicinal chemistry

Avec: Shiu-Wen Huang , Ming Jen Hsu , Hsiu-Chen Chen , Rita Meleddu , Simona Distinto , Elias Maccioni , Filippo Cottiglia

Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity.

Virus research

Avec: A Paulis , A Onali , P O Vidalain , V Lotteau , C Jaquemin , A Corona , S Distinto , G L Delogu , E Tramontano

Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function.

Antimicrobial agents and chemotherapy

Avec: Elisa Fanunza , Mathieu Iampietro , Simona Distinto , Angela Corona , Marina Quartu , Elias Maccioni , Branka Horvat , Enzo Tramontano

Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases.

Journal of enzyme inhibition and medicinal chemistry

Avec: Simona Distinto , Rita Meleddu , Francesco Ortuso , Filippo Cottiglia , Serenella Deplano , Lisa Sequeira , Claudia Melis , Benedetta Fois , Andrea Angeli , Clemente Capasso , Rossella Angius , Stefano Alcaro , Claudiu T Supuran , Elias Maccioni

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives.

Journal of enzyme inhibition and medicinal chemistry

Avec: Rita Meleddu , Serenella Deplano , Elias Maccioni , Francesco Ortuso , Filippo Cottiglia , Daniela Secci , Alessia Onali , Erica Sanna , Andrea Angeli , Rossella Angius , Stefano Alcaro , Claudiu T Supuran , Simona Distinto

Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions.

Molecules (Basel, Switzerland)

Avec: Rita Meleddu , Angela Corona , Simona Distinto , Filippo Cottiglia , Serenella Deplano , Lisa Sequeira , Daniela Secci , Alessia Onali , Erica Sanna , Francesca Esposito , Italo Cirone , Francesco Ortuso , Stefano Alcaro , Enzo Tramontano , Péter Mátyus , Elias Maccioni

Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action.

Antiviral research

Avec: Angela Corona , David Strayer , Simona Distinto , Gian Luca Daino , Annalaura Paulis , Enzo Tramontano , William M Mitchell

Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques.

European journal of medicinal chemistry

Avec: Giosuè Costa , Roberta Rocca , Angela Corona , Nicole Grandi , Federica Moraca , Isabella Romeo , Carmine Talarico , Maria Giovanna Gagliardi , Francesca Alessandra Ambrosio , Francesco Ortuso , Stefano Alcaro , Simona Distinto , Elias Maccioni , Enzo Tramontano , Anna Artese

Ferulic Acid Esters and Withanolides: In Search of Withania somnifera GABA

Journal of natural products

Avec: Vijay P Sonar , Benedetta Fois , Simona Distinto , Elias Maccioni , Rita Meleddu , Filippo Cottiglia , Elio Acquas , Sanjay Kasture , Costantino Floris , Daniele Colombo , Claudia Sissi , Enrico Sanna , Giuseppe Talani

Flavonoids and Acid-Hydrolysis derivatives of

Journal of enzyme inhibition and medicinal chemistry

Avec: Benedetta Fois , Angela Corona , Enzo Tramontano , Simona Distinto , Elias Maccioni , Rita Meleddu , Pierluigi Caboni , Costantino Floris , Filippo Cottiglia

5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action.

Frontiers in cellular and infection microbiology

Avec: Angela Corona , Rita Meleddu , Olivier Delelis , Frederic Subra , Filippo Cottiglia , Francesca Esposito , Simona Distinto , Elias Maccioni , Enzo Tramontano

2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms.

Journal of enzyme inhibition and medicinal chemistry

Avec: Lisa Sequeira , Simona Distinto , Rita Meleddu , Marco Gaspari , Andrea Angeli , Filippo Cottiglia , Daniela Secci , Alessia Onali , Erica Sanna , Fernanda Borges , Eugenio Uriarte , Stefano Alcaro , Claudiu T Supuran , Elias Maccioni

Privileged Scaffold Hybridization in the Design of Carbonic Anhydrase Inhibitors.

Molecules (Basel, Switzerland)

Avec: Daniela Secci , Erica Sanna , Simona Distinto , Alessia Onali , Antonio Lupia , Laura Demuru , Giulia Atzeni , Rita Meleddu , Filippo Cottiglia , Andrea Angeli , Claudiu T Supuran , Elias Maccioni

Réseau de co-auteurs

Elias Maccioni 16 collaborations

Rita Meleddu 13 collaborations

Filippo Cottiglia 13 collaborations

Angela Corona 9 collaborations

Enzo Tramontano 9 collaborations

Andrea Angeli 6 collaborations

Serenella Deplano 6 collaborations

Stefano Alcaro 6 collaborations

Claudiu T Supuran 6 collaborations

Alessia Onali 5 collaborations

Erica Sanna 5 collaborations

Daniela Secci 5 collaborations

Francesco Ortuso 5 collaborations

Benedetta Fois 5 collaborations

Pierluigi Caboni 4 collaborations

Rossella Angius 4 collaborations

Francesca Esposito 3 collaborations

Costantino Floris 3 collaborations

Lisa Sequeira 3 collaborations

Nicole Grandi 2 collaborations

Antonio Lupia 2 collaborations

Giulia Atzeni 2 collaborations

Laura Demuru 2 collaborations

Fernanda Borges 2 collaborations

Claudia Melis 2 collaborations

Elisa Fanunza 2 collaborations

Gian Luca Daino 2 collaborations

Marina Quartu 2 collaborations

Claudia Sissi 2 collaborations

Marco Gaspari 2 collaborations

Ester Ballana 1 collaboration

Dominga Rogolino 1 collaboration

Claudia Del Vecchio 1 collaboration

Mauro Carcelli 1 collaboration

Roger Badia 1 collaboration

Eva Riveira-Muñoz 1 collaboration

Cristina Parolin 1 collaboration

José A Esté 1 collaboration

Antonella Fais 1 collaboration

Benedetta Era 1 collaboration

Sonia Floris 1 collaboration

Donatella Valenti 1 collaboration

Diana Oliveira 1 collaboration

Anabela Borges 1 collaboration

Reinaldo Molina Ruiz 1 collaboration

Zenaida Rodríguez Negrín 1 collaboration

Manuel Simões 1 collaboration

Cristiano Salata 1 collaboration

Melody Jane Morwitzer 1 collaboration

Luca Zinzula 1 collaboration

Cinzia Sanna 1 collaboration

Aldo Frau 1 collaboration

Orazio Taglialatela-Scafati 1 collaboration

Daniela Rigano 1 collaboration

StPatrick Reid 1 collaboration

Alì Mirazimi 1 collaboration

Antonella Rosa 1 collaboration

Mariella Nieddu 1 collaboration

Vilma Petrikaite 1 collaboration

Antonella Arridu 1 collaboration

Lorenzo Serusi 1 collaboration

Laura Škarnulytė 1 collaboration

Ugnė Endriulaitytė 1 collaboration

Miglė Paškevičiu Tė 1 collaboration

Domenico Taverna 1 collaboration

Serena Massari 1 collaboration

Jenny Desantis 1 collaboration

Alessia Caredda 1 collaboration

Stefano Sabatini 1 collaboration

Giuseppe Manfroni 1 collaboration

Tommaso Felicetti 1 collaboration

Violetta Cecchetti 1 collaboration

Christophe Pannecouque 1 collaboration

Oriana Tabarrini 1 collaboration

Shiu-Wen Huang 1 collaboration

Ming Jen Hsu 1 collaboration

Hsiu-Chen Chen 1 collaboration

A Paulis 1 collaboration

A Onali 1 collaboration

P O Vidalain 1 collaboration

V Lotteau 1 collaboration

C Jaquemin 1 collaboration

A Corona 1 collaboration

S Distinto 1 collaboration

G L Delogu 1 collaboration

E Tramontano 1 collaboration

Mathieu Iampietro 1 collaboration

Branka Horvat 1 collaboration

Clemente Capasso 1 collaboration

Italo Cirone 1 collaboration

Péter Mátyus 1 collaboration

David Strayer 1 collaboration

Annalaura Paulis 1 collaboration

William M Mitchell 1 collaboration

Giosuè Costa 1 collaboration

Roberta Rocca 1 collaboration

Federica Moraca 1 collaboration

Isabella Romeo 1 collaboration

Carmine Talarico 1 collaboration

Maria Giovanna Gagliardi 1 collaboration

Francesca Alessandra Ambrosio 1 collaboration

Anna Artese 1 collaboration

Vijay P Sonar 1 collaboration

Elio Acquas 1 collaboration

Sanjay Kasture 1 collaboration

Daniele Colombo 1 collaboration

Enrico Sanna 1 collaboration

Giuseppe Talani 1 collaboration

Olivier Delelis 1 collaboration

Frederic Subra 1 collaboration

Eugenio Uriarte 1 collaboration